mouse FLNA shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Flna.
shAAV-259470
AAV-m-FLNA-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Flna (filamin, alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ABP-280; Dilp2; F730004A14Rik; filamin-1; Fln1; GENA 379
Description (Vector)
Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis.
Gene ID
192176
Gene Name (Vector)
filamin, alpha
Gene Symbol
Flna
ORF Size (aa)
7920
ORF Size (bp)
7920 bp
RefSeq ID
NM_010227
RefSeq Synonyms
NM_010227, NM_001290421, BC151024,
Species
mouse
UniGene ID
Mm.295533
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.