human GCHFR Over-expression AAV

Name 
AAV-h-GCHFR
Cat No 
AAV-209739
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GCHFR.

AAV-209739
AAV-h-GCHFR

Ready-to-use AAV expressing Human GCHFR (GTP cyclohydrolase I feedback regulator). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GFRP; HsT16933; P35
Description (Vector)
GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.
Gene ID
2644
Gene Name (Vector)
GTP cyclohydrolase I feedback regulator
Gene Symbol
GCHFR
HGNC ID
HGNC:4194
ORF Size (aa)
222
RefSeq ID
NM_005258
RefSeq Synonyms
NM_005258, BC143904, BC112264, BC112262,
Species
human
UniGene ID
Hs.631717

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.