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mouse DTX4 shRNA silencing AAV

Name 
AAV-m-DTX4-shRNA
Cat No 
shAAV-257505
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Dtx4.

shAAV-257505
AAV-m-DTX4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Dtx4 (deltex 4, E3 ubiquitin ligase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI449438; BC044798; D930042H13; RNF155
Description (Vector)
Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations (By similarity). Functions as an ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.
Gene ID
207521
Gene Name (Vector)
deltex 4, E3 ubiquitin ligase
Gene Symbol
Dtx4
ORF Size (aa)
1851
ORF Size (bp)
1851 bp
RefSeq ID
NM_172442
RefSeq Synonyms
NM_172442, BC058647,
Species
mouse
UniGene ID
Mm.477187

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.