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human INS-IGF2 shRNA silencing AAV

Name 
AAV-h-INS-IGF2-shRNA
Cat No 
shAAV-229383
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human INS-IGF2.

shAAV-229383
AAV-h-INS-IGF2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human INS-IGF2 (INS-IGF2 readthrough). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
INSIGF
Description (Vector)
This locus includes two alternatively spliced read-through transcript variants which align to the INS gene in the 5' region and to the IGF2 gene in the 3' region. One transcript is predicted to encode a protein which shares the N-terminus with the INS protein but has a distinct and longer C-terminus, whereas the other transcript is a candidate for nonsense-mediated decay (NMD). The transcripts are imprinted and are paternally expressed in the limb and eye.
Gene ID
723961
Gene Name (Vector)
INS-IGF2 readthrough
Gene Symbol
INS-IGF2
ORF Size (aa)
600
RefSeq ID
NM_001042376
RefSeq Synonyms
NM_001042376, BC153083, BC148488,
Species
human
UniGene ID
Hs.

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.