mouse DPH3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Dph3.
shAAV-257411
AAV-m-DPH3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Dph3 (diphthamine biosynthesis 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DELGIP1; DelgipP1; Desr1; KTI11; Zcsl2
Description (Vector)
Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2 and which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (By similarity)|Function: Down-regulation increases extracellular release of proteoglycans, indicating a possible role in the secretion process. Stimulates binding of GNEFR to SEC5.
Gene ID
105638
Gene Name (Vector)
diphthamine biosynthesis 3
Gene Symbol
Dph3
ORF Size (aa)
249
RefSeq ID
NM_172254
RefSeq Synonyms
NM_172254, NM_001284346, NM_001047433, BC039954, BC029910,
Species
mouse
UniGene ID
Mm.2519
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.