human DPH3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human DPH3.
shADV-207277
Ad-h-DPH3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human DPH3 (diphthamide biosynthesis 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DELGIP; DELGIP1; DESR1; DPH3A; KTI11; ZCSL2
Description (Vector)
DPH3 encodes a CSL zinc finger-containing protein that is required for dipthamide biosynthesis. The encoded protein is necessary for the initial step in the modification of a histidine residue in elongation factor-2 to diphthamide. This modified residue is a target for ADP ribosylation by the bacterial toxins diphtheria toxin and Pseudomonas exotoxin A. Alternative splicing results in multiple transcript variants that encode the same isoform.
Gene ID
285381
Gene Name (Vector)
diphthamide biosynthesis 3
Gene Symbol
DPH3
HGNC ID
HGNC:27717
ORF Size (aa)
249
RefSeq ID
NM_206831
RefSeq Synonyms
NM_206831, NM_001047434, BC010181,
Species
human
UniGene ID
Hs.388087
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.