mouse DIO2 shRNA silencing AAV

Name 
AAV-m-DIO2-shRNA
Cat No 
shAAV-257182
Availability
Immediate
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Dio2.

shAAV-257182
AAV-m-DIO2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Dio2 (deiodinase, iodothyronine, type II). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
69
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
5DII; AI324267; DIOII
Description (Vector)
Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). Essential for providing the brain with appropriate levels of T3 during the critical period of development.
Gene ID
13371
Gene Name (Vector)
deiodinase, iodothyronine, type II
Gene Symbol
Dio2
ORF Size (aa)
801
RefSeq ID
NM_010050
RefSeq Synonyms
NM_010050, BC125385, BC125383,
Species
mouse
UniGene ID
Mm.408815

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.