human GABRD Over-expression AAV

Name 
AAV-h-GABRD
Cat No 
AAV-209521
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GABRD.

AAV-209521
AAV-h-GABRD

Ready-to-use AAV expressing Human GABRD (gamma-aminobutyric acid type A receptor delta subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EIG10; EJM7; GEFSP5
Description (Vector)
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined.
Gene ID
2563
Gene Name (Vector)
gamma-aminobutyric acid type A receptor delta subunit
Gene Symbol
GABRD
HGNC ID
HGNC:4084
ORF Size (aa)
1359
ORF Size (bp)
1359 bp
RefSeq ID
NM_000815
RefSeq Synonyms
NM_000815, BC033801,
Species
human
UniGene ID
Hs.113882

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.