mouse CYSLTR1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Cysltr1.
shAAV-256584
AAV-m-CYSLTR1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Cysltr1 (cysteinyl leukotriene receptor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BB147369; Cyslt1; CysLT1R
Description (Vector)
Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.
Gene ID
58861
Gene Name (Vector)
cysteinyl leukotriene receptor 1
Gene Symbol
Cysltr1
ORF Size (aa)
1059
ORF Size (bp)
1059 bp
RefSeq ID
NM_021476
RefSeq Synonyms
NM_021476, NM_001281862, NM_001281859, BC027102,
Species
mouse
UniGene ID
Mm.287166
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.