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human CYSLTR1 shRNA silencing AAV

Name 
AAV-h-CYSLTR1-shRNA
Cat No 
shAAV-206541
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CYSLTR1.

shAAV-206541
AAV-h-CYSLTR1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CYSLTR1 (cysteinyl leukotriene receptor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CYSLT1; CYSLT1R; CYSLTR; HMTMF81
Description (Vector)
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.
Gene ID
10800
Gene Name (Vector)
cysteinyl leukotriene receptor 1
Gene Symbol
CYSLTR1
HGNC ID
HGNC:17451
ORF Size (aa)
1014
RefSeq ID
NM_006639
RefSeq Synonyms
NM_006639, NM_001282188, NM_001282187, NM_001282186, BC035750,
Species
human
UniGene ID
Hs.201300

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.