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mouse CYP8B1 shRNA silencing AAV

Name 
AAV-m-CYP8B1-shRNA
Cat No 
shAAV-256571
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Cyp8b1.

shAAV-256571
AAV-m-CYP8B1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Cyp8b1 (cytochrome P450, family 8, subfamily b, polypeptide 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha-hydroxylated C27 steroids.
Gene ID
13124
Gene Name (Vector)
cytochrome P450, family 8, subfamily b, polypeptide 1
Gene Symbol
Cyp8b1
ORF Size (aa)
1503
ORF Size (bp)
1503 bp
RefSeq ID
NM_010012
RefSeq Synonyms
NM_010012, BC049969, BC010974, BC010973,
Species
mouse
UniGene ID
Mm.20889

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.