human FZD7 Over-expression AAV

Name 
AAV-h-FZD7
Cat No 
AAV-209469
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human FZD7.

AAV-209469
AAV-h-FZD7

Ready-to-use AAV expressing Human FZD7 (frizzled class receptor 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
FzE3
Description (Vector)
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.
Gene ID
8324
Gene Name (Vector)
frizzled class receptor 7
Gene Symbol
FZD7
HGNC ID
HGNC:4045
ORF Size (aa)
1725
ORF Size (bp)
1725 bp
RefSeq ID
NM_003507
RefSeq Synonyms
NM_003507, BC015915,
Species
human
UniGene ID
Hs.173859

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.