human FUCA1 Over-expression AAV

Name
AAV-h-FUCA1

Cat No
AAV-209398

Availability
4-5 weeks

This is an AAV expressing Human FUCA1.

AAV-209398

AAV-h-FUCA1

Ready-to-use AAV expressing Human FUCA1 (fucosidase, alpha-L- 1, tissue). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

FUCA

Description (Vector)

FUCA1 is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. Mutations in this gene are associated with fucosidosis (FUCA1D), which is an autosomal recessive lysosomal storage disease. A pseudogene of this locus is present on chr 2.

Gene ID

2517

Gene Name (Vector)

fucosidase, alpha-L- 1, tissue

Gene Symbol

FUCA1

HGNC ID

HGNC:4006

ORF Size (aa)

1386

ORF Size (bp)

1386 bp

RefSeq ID

NM_000147

RefSeq Synonyms

NM_000147, BC017338,

Species

human

UniGene ID

Hs.370858

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.