mouse CASP1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Casp1.
shAAV-254551
AAV-m-CASP1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Casp1 (caspase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ICE; Il1bc
Description (Vector)
Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
Gene ID
12362
Gene Name (Vector)
caspase 1
Gene Symbol
Casp1
ORF Size (aa)
1209
RefSeq ID
NM_009807
RefSeq Synonyms
NM_009807, BC008152,
Species
mouse
UniGene ID
Mm.1051
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.