mouse CARD11 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Card11.
shAAV-254524
AAV-m-CARD11-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Card11 (caspase recruitment domain family, member 11). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
0610008L17Rik; 2410011D02Rik; BIMP3; CARMA1
Description (Vector)
Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.
Gene ID
108723
Gene Name (Vector)
caspase recruitment domain family, member 11
Gene Symbol
Card11
ORF Size (aa)
3465
ORF Size (bp)
3465 bp
RefSeq ID
NM_175362
RefSeq Synonyms
NM_175362, BC096592,
Species
mouse
UniGene ID
Mm.46187
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.