mouse ANAPC11 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Anapc11.
shAAV-252597
AAV-m-ANAPC11-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Anapc11 (anaphase promoting complex subunit 11). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110011I19Rik; R75218
Description (Vector)
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.
Gene ID
66156
Gene Name (Vector)
anaphase promoting complex subunit 11
Gene Symbol
Anapc11
ORF Size (aa)
255
RefSeq ID
NM_025389
RefSeq Synonyms
NM_025389, NM_001038230, BC023039,
Species
mouse
UniGene ID
Mm.21645
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.