human FHIT Over-expression AAV

Name
AAV-h-FHIT

Cat No
AAV-209008

Availability
4-5 weeks

This is an AAV expressing Human FHIT.

AAV-209008

AAV-h-FHIT

Ready-to-use AAV expressing Human FHIT (fragile histidine triad). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AP3Aase; FRA3B

Description (Vector)

This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.

Gene ID

2272

Gene Name (Vector)

fragile histidine triad

Gene Symbol

FHIT

HGNC ID

HGNC:3701

ORF Size (aa)

444

RefSeq ID

NM_002012

RefSeq Synonyms

NM_002012, NM_001320901, NM_001320900, NM_001320899, NM_001166243, BC032336,

Species

human

UniGene ID

Hs.715597

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.