mouse TRMT112 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Trmt112.
shAAV-250034
AAV-m-TRMT112-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Trmt112 (tRNA methyltransferase 11-2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
0610038D11Rik; Trm112p
Description (Vector)
Participates both in methylation of protein and tRNA species. The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species.
Gene ID
67674
Gene Name (Vector)
tRNA methyltransferase 11-2
Gene Symbol
Trmt112
ORF Size (aa)
375
RefSeq ID
NM_026306
RefSeq Synonyms
NM_026306, NM_001166370, BC087959, BC019418, BC016191,
Species
mouse
UniGene ID
Mm.371597
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.