human PMPCB shRNA silencing AAV

Name 
AAV-h-PMPCB-shRNA
Cat No 
shAAV-233329
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PMPCB.

shAAV-233329
AAV-h-PMPCB-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PMPCB (peptidase, mitochondrial processing beta subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Beta-MPP; MPP11; MPPB; MPPP52; P-52
Description (Vector)
PMPCB is a member of the peptidase M16 family and encodes a protein with a zinc-binding motif. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria, though it only functions as part of a heterodimeric complex.
Gene ID
9512
Gene Name (Vector)
peptidase, mitochondrial processing beta subunit
Gene Symbol
PMPCB
HGNC ID
HGNC:9119
ORF Size (aa)
1444
ORF Size (bp)
1444 bp
RefSeq ID
NM_004279
RefSeq Synonyms
NM_004279, BC014079, BC010398,
Species
human

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.