human FBXW2 Over-expression AAV

Name 
AAV-h-FBXW2
Cat No 
AAV-208834
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human FBXW2.

AAV-208834
AAV-h-FBXW2

Ready-to-use AAV expressing Human FBXW2 (F-box and WD repeat domain containing 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
FBW2; Fwd2; Md6
Description (Vector)
F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats.
Gene ID
26190
Gene Name (Vector)
F-box and WD repeat domain containing 2
Gene Symbol
FBXW2
HGNC ID
HGNC:13608
ORF Size (aa)
1365
ORF Size (bp)
1365 bp
RefSeq ID
NM_012164
RefSeq Synonyms
NM_012164, BC110334, BC018738,
Species
human
UniGene ID
Hs.494985

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.