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human KAZN shRNA silencing AAV

Name 
AAV-h-KAZN-shRNA
Cat No 
shAAV-231531
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human KAZN.

shAAV-231531
AAV-h-KAZN-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KAZN (kazrin, periplakin interacting protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
KAZ
Description (Vector)
KAZN encodes a protein that plays a role in desmosome assembly, cell adhesion, cytoskeletal organization, and epidermal differentiation. This protein co-localizes with desmoplakin and the cytolinker protein periplakin. In general, this protein localizes to the nucleus, desmosomes, cell membrane, and cortical actin-based structures. Some isoforms of this protein also associate with microtubules. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity has not been verified.
Gene ID
23254
Gene Name (Vector)
kazrin, periplakin interacting protein
Gene Symbol
KAZN
HGNC ID
HGNC:29173
ORF Size (aa)
1248
ORF Size (bp)
1248 bp
RefSeq ID
NM_201628
RefSeq Synonyms
NM_201628, NM_015209, NM_001018001, NM_001018000, NM_001017999, BC113621, BC035501,
Species
human
UniGene ID
Hs.

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.