human HDGF shRNA silencing AAV

Name 
AAV-h-HDGF-shRNA
Cat No 
shAAV-230944
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human HDGF.

shAAV-230944
AAV-h-HDGF-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HDGF (hepatoma-derived growth factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
epididymis secretory sperm binding protein; HDGF; hepatoma derived growth factor; hepatoma-derived growth factor; high mobility group protein 1-like 2; HMG1L2; HMG-1L2
Description (eCommerce)
Hepatoma-derived growth factor (HDGF) was identified as a mitogen secreted from the human hepatoma cell line Huh-7. HDGF has been found to bind DNA and to function as a transcriptional repressor.
Description (Vector)
HDGF encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. HDGF was thought initially to be located on chromosome X, however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Gene ID
3068
Gene Name (eCommerce)
heparin binding growth factor
Gene Name (Vector)
hepatoma-derived growth factor
Gene Symbol
HDGF
HGNC ID
HGNC:4856
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
723
ORF Size (bp)
723 bp
Protein Name (eCommerce)
Hepatoma-derived growth factor
RefSeq ID
NM_004494
RefSeq Synonyms
NM_004494, NM_001319188, NM_001319187, NM_001319186, NM_001126051, NM_001126050, BC018991,
Research Areas
Signal Transduction,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,signal_transduction,transcription_translation
Species
human
Target Sentence
Hepatoma-derived growth factor (HDGF) was identified as a mitogen secreted from the human hepatoma cell line Huh-7. HDGF has been found to bind DNA and to function as a transcriptional repressor.
UniGene ID
Hs.506748
UniProt ID (eCommerce)
P51858

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.