human PTPRS shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PTPRS.
shAAV-230650
AAV-h-PTPRS-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PTPRS (protein tyrosine phosphatase, receptor type S). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PTPSIGMA; R-PTP-S; R-PTP-sigma
Description (Vector)
PTPRS is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.
Gene ID
5802
Gene Name (Vector)
protein tyrosine phosphatase, receptor type S
Gene Symbol
PTPRS
HGNC ID
HGNC:9681
ORF Size (aa)
4506
ORF Size (bp)
4506 bp
RefSeq ID
NM_002850
RefSeq Synonyms
NM_130855, NM_130854, NM_130853, NM_002850, BC143287, BC104812, BC029496,
Species
human
UniGene ID
Hs.644384
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.