human COPB2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human COPB2.
shAAV-229760
AAV-h-COPB2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human COPB2 (coatomer protein complex subunit beta 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
beta'-coat protein; beta'-COP; betaprime-COP; coatomer binding complex, beta prime subunit; coatomer protein complex subunit beta prime; coatomer protein complex, subunit beta 2 (beta prime); coatomer subunit beta'; MCPH19; p102
Description (eCommerce)
In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP [taken from NCBI Entrez Gene (Gene ID: 9276)].
Description (Vector)
The Golgi coatomer complex (see MIM 601924) constitutes the coat of nonclathrin-coated vesicles and is essential for Golgi budding and vesicular trafficking. It consists of 7 protein subunits, including COPB2.(supplied by OMIM, Jul 2002)
Gene ID
9276
Gene Name (eCommerce)
coatomer protein complex subunit beta 2
Gene Name (Vector)
coatomer protein complex subunit beta 2
Gene Symbol
COPB2
HGNC ID
HGNC:2232
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2721
ORF Size (bp)
2721 bp
Protein Name (eCommerce)
Coatomer subunit beta'
RefSeq ID
NM_004766
RefSeq Synonyms
NM_004766, BC000326,
Research Areas
Cytoskeleton,Golgi Apparatus,Metabolism/Metabolic Process,Signal Transduction,TNF Signaling,Transport
Research Areas (Faceted)
signal_transduction,cell_biology,metabolism,signal_transduction,cell_biology
Species
human
Target Sentence
In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP [taken from NCBI Entrez Gene (Gene ID: 9276)].
UniGene ID
Hs.719115
UniProt ID (eCommerce)
P35606
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.