human RPAP3 shRNA silencing AAV

Name 
AAV-h-RPAP3-shRNA
Cat No 
shAAV-229739
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RPAP3.

shAAV-229739
AAV-h-RPAP3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RPAP3 (RNA polymerase II associated protein 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
hSpagh; RNA polymerase II-associated protein 3; Tah1
Description (eCommerce)
RNA polymerase II-associated protein 3 (RPAP3) forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H6T3].
Description (Vector)
RPAP3 encodes an RNA polymerase II-associated protein. The encoded protein may function in transcriptional regulation and may also regulate apoptosis. Alternatively spliced transcript variants have been described.
Gene ID
79657
Gene Name (eCommerce)
RNA polymerase II associated protein 3
Gene Name (Vector)
RNA polymerase II associated protein 3
Gene Symbol
RPAP3
HGNC ID
HGNC:26151
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1896
ORF Size (bp)
1896 bp
Protein Name (eCommerce)
RNA polymerase II-associated protein 3
RefSeq ID
NM_024604
RefSeq Synonyms
NM_024604, NM_001146076, NM_001146075, BC056415,
Research Areas
Cell Biology,Translational Control
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
RNA polymerase II-associated protein 3 (RPAP3) forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H6T3].
UniGene ID
Hs.437855
UniProt ID (eCommerce)
Q9H6T3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.