human FBXL2 Over-expression AAV

Name 
AAV-h-FBXL2
Cat No 
AAV-208758
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human FBXL2.

AAV-208758
AAV-h-FBXL2

Ready-to-use AAV expressing Human FBXL2 (F-box and leucine rich repeat protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
FBL2; FBL3
Description (Vector)
FBXL2 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
25827
Gene Name (Vector)
F-box and leucine rich repeat protein 2
Gene Symbol
FBXL2
HGNC ID
HGNC:13598
ORF Size (aa)
1272
ORF Size (bp)
1272 bp
RefSeq ID
NM_012157
RefSeq Synonyms
NM_012157, NM_001171713, BC031556,
Species
human
UniGene ID
Hs.475872

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.