human FBXL2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human FBXL2.
shAAV-208758
AAV-h-FBXL2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human FBXL2 (F-box and leucine rich repeat protein 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FBL2; FBL3
Description (Vector)
FBXL2 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
25827
Gene Name (Vector)
F-box and leucine rich repeat protein 2
Gene Symbol
FBXL2
HGNC ID
HGNC:13598
ORF Size (aa)
1272
ORF Size (bp)
1272 bp
RefSeq ID
NM_012157
RefSeq Synonyms
NM_012157, NM_001171713, BC031556,
Species
human
UniGene ID
Hs.475872
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.