human WIF1 shRNA silencing AAV

Name 
AAV-h-WIF1-shRNA
Cat No 
shAAV-227788
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human WIF1.

shAAV-227788
AAV-h-WIF1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human WIF1 (WNT inhibitory factor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
WIF-1
Description (Vector)
WIF1 functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers.
Gene ID
11197
Gene Name (Vector)
WNT inhibitory factor 1
Gene Symbol
WIF1
HGNC ID
HGNC:18081
ORF Size (aa)
1140
RefSeq ID
NM_007191
RefSeq Synonyms
NM_007191, BC018037,
Species
human
UniGene ID
Hs.284122

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.