human WDR7 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human WDR7.
shAAV-227718
AAV-h-WDR7-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human WDR7 (WD repeat domain 7). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
TRAG
Description (Vector)
WDR7 encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) that may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. The encoded protein forms the beta subunit of rabconnectin-3 and binds directly with Rab3A GDP/GTP exchange protein and indirectly with Rab3A GDP/GTP activating protein; these proteins are regulators of Rab3 small G protein family members involved in control of the calcium-dependant exocytosis of neurotransmitters. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene ID
23335
Gene Name (Vector)
WD repeat domain 7
Gene Symbol
WDR7
HGNC ID
HGNC:13490
ORF Size (aa)
2448
ORF Size (bp)
2448 bp
RefSeq ID
NM_015285
RefSeq Synonyms
NM_052834, NM_015285, BC150282, BC131558,
Species
human
UniGene ID
Hs.465213
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.