human UNC119 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human UNC119.
shAAV-227180
AAV-h-UNC119-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human UNC119 (unc-119 lipid binding chaperone). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HRG4; IMD13; POC7; POC7A
Description (Vector)
UNC119 is specifically expressed in the photoreceptors in the retina. The encoded product shares strong homology with the C. elegans unc119 protein and it can functionally complement the C. elegans unc119 mutation. It has been localized to the photoreceptor synapses in the outer plexiform layer of the retina, and suggested to play a role in the mechanism of photoreceptor neurotransmitter release through the synaptic vesicle cycle. Two transcript variants encoding different isoforms have been described for this gene.
Gene ID
9094
Gene Name (Vector)
unc-119 lipid binding chaperone
Gene Symbol
UNC119
HGNC ID
HGNC:12565
ORF Size (aa)
723
RefSeq ID
NM_005148
RefSeq Synonyms
NM_054035, NM_005148, NM_001330166, BC027176,
Species
human
UniGene ID
Hs.410455
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.