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human TYMP shRNA silencing AAV

Name 
AAV-h-TYMP-shRNA
Cat No 
shAAV-226933
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TYMP.

shAAV-226933
AAV-h-TYMP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TYMP (thymidine phosphorylase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ECGF; ECGF1; hPD-ECGF; MEDPS1; MNGIE; MTDPS1; PDECGF; TP
Description (Vector)
TYMP encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified.
Gene ID
1890
Gene Name (Vector)
thymidine phosphorylase
Gene Symbol
TYMP
HGNC ID
HGNC:3148
ORF Size (aa)
1449
ORF Size (bp)
1449 bp
RefSeq ID
NM_001953
RefSeq Synonyms
NM_001953, NM_001257989, NM_001257988, NM_001113756, NM_001113755, BC052211, BC018160,
Species
human
UniGene ID
Hs.592212

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.