human TWIST2 shRNA silencing AAV

Name 
AAV-h-TWIST2-shRNA
Cat No 
shAAV-226881
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TWIST2.

shAAV-226881
AAV-h-TWIST2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TWIST2 (twist family bHLH transcription factor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AMS; BBRSAY; bHLHa39; DERMO1; FFDD3; SETLSS
Description (Vector)
Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. The protein encoded by this gene is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Twist. It is thought that during osteoblast development this protein may inhibit osteoblast maturation and maintain cells in a preosteoblast phenotype.
Gene ID
117581
Gene Name (Vector)
twist family bHLH transcription factor 2
Gene Symbol
TWIST2
HGNC ID
HGNC:20670
ORF Size (aa)
483
ORF Size (bp)
483 bp
RefSeq ID
NM_057179
RefSeq Synonyms
NM_057179, NM_001271893, BC103755, BC033168, BC017907,
Species
human
UniGene ID
Hs.708196

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.