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human TSSC1 shRNA silencing AAV

Name 
AAV-h-TSSC1-shRNA
Cat No 
shAAV-226665
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TSSC1.

shAAV-226665
AAV-h-TSSC1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TSSC1 (tumor suppressing subtransferable candidate 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EIPR1
Description (Vector)
TSSC1 has been reported in PMID 9403053 as one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alignment of this gene to genomic sequence data suggests that this gene resides on chromosome 2 rather than chromosome 11.
Gene ID
7260
Gene Name (Vector)
tumor suppressing subtransferable candidate 1
Gene Symbol
TSSC1
HGNC ID
HGNC:12383
ORF Size (aa)
1164
RefSeq ID
NM_003310
RefSeq Synonyms
NM_003310, NM_001330531, NM_001330530, BC002485,
Species
human
UniGene ID
Hs.502770

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.