human TRPV1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TRPV1.
shAAV-226561
AAV-h-TRPV1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TRPV1 (transient receptor potential cation channel subfamily V member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
VR1
Description (Vector)
Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene.
Gene ID
7442
Gene Name (Vector)
transient receptor potential cation channel subfamily V member 1
Gene Symbol
TRPV1
HGNC ID
HGNC:12716
ORF Size (aa)
2520
ORF Size (bp)
2520 bp
RefSeq ID
NM_018727
RefSeq Synonyms
NM_080706, NM_080705, NM_080704, NM_018727, BC136633, BC132820,
Species
human
UniGene ID
Hs.655380
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.