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human TRPM6 shRNA silencing AAV

Name 
AAV-h-TRPM6-shRNA
Cat No 
shAAV-226557
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TRPM6.

shAAV-226557
AAV-h-TRPM6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TRPM6 (transient receptor potential cation channel subfamily M member 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CHAK2; HMGX; HOMG; HOMG1; HSH
Description (Vector)
TRPM6 is predominantly expressed in the kidney and colon, and encodes a protein containing an ion channel domain and a protein kinase domain. It is crucial for magnesium homeostasis, and plays an essential role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Mutations in this gene are associated with hypomagnesemia with secondary hypocalcemia. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Gene ID
140803
Gene Name (Vector)
transient receptor potential cation channel subfamily M member 6
Gene Symbol
TRPM6
HGNC ID
HGNC:17995
ORF Size (aa)
6066
ORF Size (bp)
6066 bp
RefSeq ID
NM_017662
RefSeq Synonyms
NM_017662, NM_001177311, NM_001177310, BC156137,
Species
human
UniGene ID
Hs.272225

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.