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human TRPM6 shRNA silencing Adenovirus

Name 
Ad-h-TRPM6-shRNA
Cat No 
shADV-226557
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human TRPM6.

shADV-226557
Ad-h-TRPM6-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TRPM6 (transient receptor potential cation channel subfamily M member 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CHAK2; HMGX; HOMG; HOMG1; HSH
Description (Vector)
TRPM6 is predominantly expressed in the kidney and colon, and encodes a protein containing an ion channel domain and a protein kinase domain. It is crucial for magnesium homeostasis, and plays an essential role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Mutations in this gene are associated with hypomagnesemia with secondary hypocalcemia. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Gene ID
140803
Gene Name (Vector)
transient receptor potential cation channel subfamily M member 6
Gene Symbol
TRPM6
HGNC ID
HGNC:17995
ORF Size (aa)
6066
ORF Size (bp)
6066 bp
RefSeq ID
NM_017662
RefSeq Synonyms
NM_017662, NM_001177311, NM_001177310, BC156137,
Species
human
UniGene ID
Hs.272225

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.