human TRAPPC2 shRNA silencing AAV

Name
AAV-h-TRAPPC2-shRNA

Cat No
shAAV-226350

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human TRAPPC2.

shAAV-226350

AAV-h-TRAPPC2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TRAPPC2 (trafficking protein particle complex 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

hYP38334; MIP2A; SEDL; SEDT; TRAPPC2P1; TRS20; ZNF547L

Description (Vector)

TRAPPC2 is thought to be part of a large multi-subunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind c-myc promoter-binding protein 1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseudogenes are found on chromosomes 8 and Y. Alternatively spliced transcript variants have been found for this gene.

Gene ID

6399

Gene Name (Vector)

trafficking protein particle complex 2

Gene Symbol

TRAPPC2

HGNC ID

HGNC:23068

ORF Size (aa)

423

RefSeq ID

NM_014563

RefSeq Synonyms

NM_014563, NM_001128835, NM_001011658, BC052618, BC016915,

Species

human

UniGene ID

Hs.622292

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.