human FAM175A Over-expression AAV

Name 
AAV-h-FAM175A
Cat No 
AAV-208489
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human FAM175A.

AAV-208489
AAV-h-FAM175A

Ready-to-use AAV expressing Human FAM175A (family with sequence similarity 175 member A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ABRA1; abraxas protein; BRCA1-A complex subunit Abraxas; BRCA1-A complex subunit Abraxas 1; CCDC98; coiled-coil domain containing 98; Coiled-coil domain-containing protein 98; FAM175A; family with sequence similarity 175 member A; Protein FAM175A
Description (eCommerce)
Abraxas was identified in a phosphopeptide affinity proteomic and mass spec analysis as a protein that bound directly to the BRCA1 BRCT repeat. Along with RAP80, Abraxas was required to form a complex with BRCA1 for the DNA damage response.
Gene ID
84142
Gene Name (eCommerce)
abraxas 1, BRCA1 A complex subunit
Gene Name (Vector)
family with sequence similarity 175 member A
Gene Symbol
FAM175A
HGNC ID
HGNC:25829
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
903
ORF Size (bp)
903 bp
Protein Name (eCommerce)
BRCA1-A complex subunit Abraxas
RefSeq ID
NM_139076
RefSeq Synonyms
NM_139076, NM_001345962, BC039573, BC016905,
Research Areas
Cell Biology,Cell Cycle,DNA Damage/Repair,Homologous Recombination,Signal Transduction,Ubiquitination
Research Areas (Faceted)
signal_transduction,cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
Abraxas was identified in a phosphopeptide affinity proteomic and mass spec analysis as a protein that bound directly to the BRCA1 BRCT repeat. Along with RAP80, Abraxas was required to form a complex with BRCA1 for the DNA damage response.
UniGene ID
Hs.334772
UniProt ID (eCommerce)
Q6UWZ7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.