human TNIP2 shRNA silencing AAV

Name
AAV-h-TNIP2-shRNA

Cat No
shAAV-226118

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human TNIP2.

shAAV-226118

AAV-h-TNIP2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TNIP2 (TNFAIP3 interacting protein 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ABIN2; FLIP1; KLIP

Description (Vector)

TNIP2 binds to the C-terminal zinc finger domain of A20 (TNFAIP3; MIM 191163) and is involved in activation of the ERK (see MAPK3; MIM 601795) MAP kinase pathway in various cell types (Van Huffel et al., 2001 (PubMed 11390377); Papoutsopoulou et al., 2006 (PubMed 16633345)).(supplied by OMIM, Mar 2008)

Gene ID

79155

Gene Name (Vector)

TNFAIP3 interacting protein 2

Gene Symbol

TNIP2

HGNC ID

HGNC:19118

ORF Size (aa)

1290

ORF Size (bp)

1290 bp

RefSeq ID

NM_024309

RefSeq Synonyms

NM_024309, NM_001292016, NM_001161527, BC002740,

Species

human

UniGene ID

Hs.368551

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.