human TMEM109 shRNA silencing AAV

Name 
AAV-h-TMEM109-shRNA
Cat No 
shAAV-225705
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TMEM109.

shAAV-225705
AAV-h-TMEM109-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TMEM109 (transmembrane protein 109). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
mg23; mitsugumin-23; transmembrane protein 109
Description (eCommerce)
Transmembrane protein 109 (TMEM109) may mediate cellular response to DNA damage by protecting against ultraviolet C-induced cell death (PubMed:23542032).TMEM109 can form voltage-gated calcium and potassium channels in vitro (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BVC6].
Gene ID
79073
Gene Name (eCommerce)
transmembrane protein 109
Gene Name (Vector)
transmembrane protein 109
Gene Symbol
TMEM109
HGNC ID
HGNC:28771
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
732
ORF Size (bp)
732 bp
Protein Name (eCommerce)
Transmembrane protein 109
RefSeq ID
NM_024092
RefSeq Synonyms
NM_024092, BC001309,
Research Areas
Immunology,Signal Transduction
Research Areas (Faceted)
signal_transduction,immunology
Species
human
Target Sentence
Transmembrane protein 109 (TMEM109) may mediate cellular response to DNA damage by protecting against ultraviolet C-induced cell death (PubMed:23542032).TMEM109 can form voltage-gated calcium and potassium channels in vitro (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BVC6].
UniGene ID
Hs.13662
UniProt ID (eCommerce)
Q9BVC6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.