human THPO shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human THPO.
shAAV-225462
AAV-h-THPO-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human THPO (thrombopoietin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MGDF; MKCSF; ML; MPLLG; THCYT1; TPO
Description (Vector)
Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternate splicing results in multiple transcript variants of this gene.
Gene ID
7066
Gene Name (Vector)
thrombopoietin
Gene Symbol
THPO
HGNC ID
HGNC:11795
ORF Size (aa)
1050
ORF Size (bp)
1050 bp
RefSeq ID
NM_000460
RefSeq Synonyms
NM_001290028, NM_001290027, NM_001290026, NM_001290022, NM_001290003, NM_001289998, NM_001289997, NM_001177598, NM_001177597, NM_000460, BC143982, BC136338, BC130322,
Species
human
UniGene ID
Hs.1166
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.