human THOC7 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human THOC7.
shAAV-225457
AAV-h-THOC7-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human THOC7 (THO complex 7). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
fSAP24; functional spliceosome-associated protein 24; hTREX30; Ngg1 interacting factor 3 like 1 binding protein 1; ngg1-interacting factor 3-like protein 1-binding protein 1; NIF3L1-binding protein 1; NIF3L1BP1; THO complex 7 homolog; THO complex subunit 7 homolog
Description (eCommerce)
THO complex subunit 7 homolog, encoded by the gene THOC7, is required for efficient export of polyadenylated RNA. THOC7 acts as a component of the THO subcomplex of the TREX complex. This complex is thought to couple mRNA transcription, processing and nuclear export [taken from UniProtKB (Entry: Q6I9Y2)].
Gene ID
80145
Gene Name (eCommerce)
THO complex 7
Gene Name (Vector)
THO complex 7
Gene Symbol
THOC7
HGNC ID
HGNC:29874
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
615
ORF Size (bp)
615 bp
Protein Name (eCommerce)
THO complex subunit 7 homolog
RefSeq ID
NM_025075
RefSeq Synonyms
NM_025075, NM_001285404, NM_001285387, BC065012,
Research Areas
Host-Virus Interactions,mRNA Processing,mRNA Splicing,mRNA transport,RNA Binding,RNA Processing,RNA Transport
Research Areas (Faceted)
infectious_disease,genetics,transcription_translation,cell_biology
Species
human
Target Sentence
THO complex subunit 7 homolog, encoded by the gene THOC7, is required for efficient export of polyadenylated RNA. THOC7 acts as a component of the THO subcomplex of the TREX complex. This complex is thought to couple mRNA transcription, processing and nuclear export [taken from UniProtKB (Entry: Q6I9Y2)].
UniGene ID
Hs.288151
UniProt ID (eCommerce)
Q6I9Y2
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.