human TFAP2A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TFAP2A.
shAAV-225344
AAV-h-TFAP2A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TFAP2A (transcription factor AP-2 alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AP-2; AP-2alpha; AP2TF; BOFS; TFAP2
Description (Vector)
TFAP2A is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.
Gene ID
7020
Gene Name (Vector)
transcription factor AP-2 alpha
Gene Symbol
TFAP2A
HGNC ID
HGNC:11742
ORF Size (aa)
1296
ORF Size (bp)
1296 bp
RefSeq ID
NM_003220
RefSeq Synonyms
NM_003220, NM_001042425, NM_001032280, BC017754,
Species
human
UniGene ID
Hs.519880
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.