human TBCD shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TBCD.
shAAV-225119
AAV-h-TBCD-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TBCD (tubulin folding cofactor D). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PEBAT; SSD-1; tfcD
Description (Vector)
Cofactor D is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
Gene ID
6904
Gene Name (Vector)
tubulin folding cofactor D
Gene Symbol
TBCD
HGNC ID
HGNC:11581
ORF Size (aa)
2253
ORF Size (bp)
2253 bp
RefSeq ID
NM_005993
RefSeq Synonyms
NM_005993, BC039654, BC006364, BC003094,
Species
human
UniGene ID
Hs.464391
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.