human TASP1 shRNA silencing AAV

Name
AAV-h-TASP1-shRNA

Cat No
shAAV-225041

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human TASP1.

shAAV-225041

AAV-h-TASP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TASP1 (taspase 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

C20orf13; dJ585I14.2

Description (Vector)

TASP1 encodes an endopeptidase that cleaves specific substrates following aspartate residues. The encoded protein undergoes posttranslational autoproteolytic processing to generate alpha and beta subunits, which reassemble into the active alpha2-beta2 heterotetramer. It is required to cleave MLL, a protein required for the maintenance of HOX gene expression, and TFIIA, a basal transcription factor. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Gene ID

55617

Gene Name (Vector)

taspase 1

Gene Symbol

TASP1

HGNC ID

HGNC:15859

ORF Size (aa)

1263

ORF Size (bp)

1263 bp

RefSeq ID

NM_017714

RefSeq Synonyms

NM_017714, NM_001323604, NM_001323603, NM_001323602, BC025266,

Species

human

UniGene ID

Hs.640471

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.