human TASP1 shRNA silencing Adenovirus

Name 
Ad-h-TASP1-shRNA
Cat No 
shADV-225041
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human TASP1.

shADV-225041
Ad-h-TASP1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TASP1 (taspase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C20orf13; dJ585I14.2
Description (Vector)
TASP1 encodes an endopeptidase that cleaves specific substrates following aspartate residues. The encoded protein undergoes posttranslational autoproteolytic processing to generate alpha and beta subunits, which reassemble into the active alpha2-beta2 heterotetramer. It is required to cleave MLL, a protein required for the maintenance of HOX gene expression, and TFIIA, a basal transcription factor. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Gene ID
55617
Gene Name (Vector)
taspase 1
Gene Symbol
TASP1
HGNC ID
HGNC:15859
ORF Size (aa)
1263
ORF Size (bp)
1263 bp
RefSeq ID
NM_017714
RefSeq Synonyms
NM_017714, NM_001323604, NM_001323603, NM_001323602, BC025266,
Species
human
UniGene ID
Hs.640471

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.