human SYNGAP1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SYNGAP1.
shAAV-224811
AAV-h-SYNGAP1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SYNGAP1 (synaptic Ras GTPase activating protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MRD5; RASA1; RASA5; SYNGAP
Description (Vector)
SYNGAP1 is a major component of the postsynaptic density (PSD), a group of proteins found associated with NMDA receptors at synapses. The encoded protein is phosphorylated by calmodulin-dependent protein kinase II and dephosphorylated by NMDA receptor activation. Defects in this gene are a cause of mental retardation autosomal dominant type 5 (MRD5).
Gene ID
8831
Gene Name (Vector)
synaptic Ras GTPase activating protein 1
Gene Symbol
SYNGAP1
HGNC ID
HGNC:11497
ORF Size (aa)
3984
ORF Size (bp)
3984 bp
RefSeq ID
NM_006772
RefSeq Synonyms
NM_006772, NM_001130066, BC148357,
Species
human
UniGene ID
Hs.586264
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.