human SYNGAP1 shRNA silencing Adenovirus

Name 
Ad-h-SYNGAP1-shRNA
Cat No 
shADV-224811
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SYNGAP1.

shADV-224811
Ad-h-SYNGAP1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SYNGAP1 (synaptic Ras GTPase activating protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
MRD5; RASA1; RASA5; SYNGAP
Description (Vector)
SYNGAP1 is a major component of the postsynaptic density (PSD), a group of proteins found associated with NMDA receptors at synapses. The encoded protein is phosphorylated by calmodulin-dependent protein kinase II and dephosphorylated by NMDA receptor activation. Defects in this gene are a cause of mental retardation autosomal dominant type 5 (MRD5).
Gene ID
8831
Gene Name (Vector)
synaptic Ras GTPase activating protein 1
Gene Symbol
SYNGAP1
HGNC ID
HGNC:11497
ORF Size (aa)
3984
ORF Size (bp)
3984 bp
RefSeq ID
NM_006772
RefSeq Synonyms
NM_006772, NM_001130066, BC148357,
Species
human
UniGene ID
Hs.586264

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.