human FAM120A Over-expression AAV

Name
AAV-h-FAM120A

Cat No
AAV-208353

Availability
4-5 weeks

This is an AAV expressing Human FAM120A.

AAV-208353

AAV-h-FAM120A

Ready-to-use AAV expressing Human FAM120A (family with sequence similarity 120A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

C9orf10; constitutive coactivator of PPAR-gamma-like protein 1; HBVPTPAP; OSSA; oxidative stess-associated Src activator; oxidative stress-associated Src activator; Protein FAM120A

Description (eCommerce)

Oxidative stress-associated Src activator (OSSA) may participate in mRNA transport in the cytoplasm (by similarity). OSSA is a critical component of the oxidative stress-induced survival signaling. It activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. It binds RNA and promotes the secretion of IGF-II. OSSA may play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NZB2].

Gene ID

23196

Gene Name (eCommerce)

family with sequence similarity 120A

Gene Name (Vector)

family with sequence similarity 120A

Gene Symbol

FAM120A

HGNC ID

HGNC:13247

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

3357

ORF Size (bp)

3357 bp

Protein Name (eCommerce)

Constitutive coactivator of PPAR-gamma-like protein 1

RefSeq ID

NM_014612

RefSeq Synonyms

NM_014612, NM_001286724, NM_001286723, NM_001286722, BC111736, BC098584,

Research Areas

Cancer,RNA Binding,Transport,Tumor Suppressors/Oncoproteins

Research Areas (Faceted)

cancer,cell_biology

Species

human

Target Sentence

Oxidative stress-associated Src activator (OSSA) may participate in mRNA transport in the cytoplasm (by similarity). OSSA is a critical component of the oxidative stress-induced survival signaling. It activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. It binds RNA and promotes the secretion of IGF-II. OSSA may play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NZB2].

UniGene ID

Hs.707324

UniProt ID (eCommerce)

Q9NZB2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.