human STK11 shRNA silencing AAV

Name
AAV-h-STK11-shRNA

Cat No
shAAV-224574

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human STK11.

shAAV-224574

AAV-h-STK11-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human STK11 (serine/threonine kinase 11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

hLKB1; LKB1; PJS

Description (Vector)

This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Gene ID

6794

Gene Name (Vector)

serine/threonine kinase 11

Gene Symbol

STK11

HGNC ID

HGNC:11389

ORF Size (aa)

1302

ORF Size (bp)

1302 bp

RefSeq ID

NM_000455

RefSeq Synonyms

NM_000455, BC019334, BC007981,

Species

human

UniGene ID

Hs.515005

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.